Effects of atrial natriuretic factor in rats with experimental high-output heart failure
نویسندگان
چکیده
منابع مشابه
Renal function in high-output heart failure in rats: role of endogenous natriuretic peptides.
The physiologic and pathophysiologic importance of natriuretic peptides (NP) has been imperfectly defined. The diminished renal responses to exogenous atrial NP in heart failure have led to the perception that the endogenous NP system might be less effective and thus contribute to renal sodium retention in heart failure. This study tests the hypothesis that in experimental heart failure, the re...
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This study was designed to address three objectives in an experimental model of acute congestive heart failure (CHF) in the dog produced by rapid ventricular pacing. The first objective was to characterize cardiorenal and humoral responses before and during 2 h of acute CHF. The second objective was to determine the modulating action of iv furosemide upon these biologic responses to acute CHF, ...
متن کاملResponse of Atrial Natriuretic Factor to Acute and Chronic Increases of Atrial Pressures in Experimental Heart Failure in Dogs
Background. This study evaluated the role of changes in heart rate, atrial pressure, volume, and cardiac tissue atrial natriuretic factor (ANF) concentration in the modulation of plasma ANF concentration in a model of pacing-induced heart failure. Methods and Results. The effects of acute right ventricular pacing (250 beats/min), acute volume expansion (35 ml/mmn), and volume expansion after 1 ...
متن کاملIntra-Arterial Atrial Natriuretic Peptide in Patients With Heart Failure
It has been shown that renal responses to atrial natriuretic peptide (ANP) are markedly attenuated in patients with heart failure. This study aimed to determine if vasodilative response to ANP is altered in patients with heart failure. In patients with heart failure (n=7) and age-matched normal subjects (n=7), forearm blood flow was measured using a strain-gauge plethysmograph during intra-arte...
متن کاملHigh output heart failure.
The symptoms and signs of heart failure can occur in the setting of an increased cardiac output and has been termed 'high output heart failure'. An elevated cardiac output with clinical heart failure is associated with several diseases including chronic anaemia, systemic arterio-venous fistulae, sepsis, hypercapnia and hyperthyroidism. The underlying primary physiological problem is of reduced ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1988
ISSN: 0085-2538
DOI: 10.1038/ki.1988.49